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Intraoperative fluorescent staining combined with microsurgery for gliomas

Prospective study of the effect of intraoperative fluorescent staining combined with microscopy on the prognosis of patients with gliomas

Status
Recruiting
Phases
Unknown
Study type
Observational
Source
ChiCTR
Registry ID
ChiCTR2500113194
Enrollment
Unknown
Registered
2025-11-26
Start date
2024-09-05
Completion date
Unknown
Last updated
2025-12-01

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

glioma

Interventions

Microscopic observation fluorescence staining group (experimental group)
:None

Sponsors

The First Affiliated Hospital,Sun Yat-sen University
Lead Sponsor

Eligibility

Sex/Gender
All
Age
18 Years to 60 Years

Inclusion criteria

Inclusion criteria: 1. any gender, age 18-60 years old; 2. patients with a confirmed diagnosis of glioma (primary tumor or metastatic tumor) by imaging or biopsy; 3. patients who can tolerate the surgery by preoperative evaluation; the expected volume of tumor specimen to be resected intraoperatively is more than 1cm^3; 4. subjects who voluntarily enroll in the study, sign the informed consent form, and have a good adherence to the study and cooperate with the follow-up visits; 5. patients with expected survival of not less than 12 months as judged by clinician; and 6. patients who are not in the clinical trial. The expected survival period, as judged by the clinician, is not less than 12 months.

Exclusion criteria

Exclusion criteria: 1.Serious or unstable diseases of the heart, lungs, kidneys and hematopoietic system that cannot tolerate surgery; 2.Pregnant or lactating women; 3.Other factors that, in the judgment of the investigator, could lead to termination of the study, such as other serious medical conditions or serious laboratory abnormalities or other family or social factors that would affect the safety of the subject or the collection of test data and samples.

Design outcomes

Primary

MeasureTime frame
overall survival (OS);

Secondary

MeasureTime frame
progression-free survival (PFS);

Countries

China

Contacts

Public ContactZhang Nu

The First Affiliated Hospital,Sun Yat-sen University

zhangnu2@mail.sysu.edu.cn+86 138 2507 0717

Outcome results

None listed

Source: ChiCTR (via WHO ICTRP) · Data processed: Feb 4, 2026