Brain-organ metabolic axis
Conditions
Interventions
Sponsors
Eligibility
Inclusion criteria
Inclusion criteria: 1. Patients who have no obvious lesions after undergoing 18F-FDG PET/CT whole-brain and whole-body imaging in our hospital for physical examination or personal reasons; 2. No other general medical history in the recent period (within 6 months); 3. No history of tumors; 4. Aged >= 18 years, regardless of gender; 5. Complete clinical data (including medical history, laboratory tests, imaging reports, etc.); 6. The image quality of 18F-FDG PET/CT imaging meets the analysis requirements (no obvious motion artifacts, uniform radioactive distribution).
Exclusion criteria
Exclusion criteria: 1. Patients with diseases that may significantly affect systemic metabolism, such as severe liver and kidney failure, end-stage malignant tumors, etc.; 2. Patients who have received radiotherapy, chemotherapy, or immunosuppressant therapy; 3. Presence of organic brain lesions (such as cerebral infarction, acute phase of cerebral hemorrhage) or other conditions that interfere with the assessment of brain metabolism; 4. Unqualified image quality (e.g., insufficient resolution, artifacts affecting region recognition); 5. Key information is missing from clinical data (e.g., unrecorded medical history, lack of laboratory test results).
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| relative coefficient;Maximum standardized uptake value; | — |
Secondary
| Measure | Time frame |
|---|---|
| Intraclass Correlation Coefficient; | — |
Countries
China
Contacts
Peking University Shenzhen Hospital