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Comparison of Bupivacaine Liposomal Paravertebral Nerve Block and Epidural Analgesia in Hepatectomy

Comparison of Bupivacaine Liposomal Paravertebral Nerve Block and Epidural Analgesia in Hepatectomy

Status
Active, not recruiting
Phases
Unknown
Study type
Interventional
Source
ChiCTR
Registry ID
ChiCTR2500113168
Enrollment
Unknown
Registered
2025-11-25
Start date
2025-12-01
Completion date
Unknown
Last updated
2025-12-01

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Postoperative Analgesia in Patients with Hepatic Malignant Tumors

Interventions

Control group:Epidural Bupivacaine Group
Experimental group:Liposomal Bupivacaine Paravertebral Block Group

Sponsors

Zhejiang Cancer Hospital
Lead Sponsor

Eligibility

Sex/Gender
All
Age
18 Years to No maximum

Inclusion criteria

Inclusion criteria: 1.Age over 18 years; 2.ASA (American Society of Anesthesiologists) physical status classification of I to III; 3.Child-Pugh liver function classification of grade A or B; 4.No history of allergy to the drugs used in this study; 5.Patients scheduled for elective or scheduled open partial hepatectomy; 6.Ability to communicate effectively and willingness to participate in the study.

Exclusion criteria

Exclusion criteria: 1.Patients with contraindications to epidural or paravertebral nerve block; 2.Patients receiving therapeutic anticoagulation, chronic opioid therapy, or those with a history of substance abuse or alcohol abuse; 3.Pregnancy.

Design outcomes

Primary

MeasureTime frame
Overall Benefit of Analgesia Score over the first 3 postoperative days in both groups;

Countries

China

Contacts

Public ContactMan Fang

Zhejiang Cancer Hospital

fangman1419@163.com+86 571 88122106

Outcome results

None listed

Source: ChiCTR (via WHO ICTRP) · Data processed: Feb 4, 2026