Papillary thyroid carcinoma
Conditions
Interventions
Trial Group:Mitoxantrone hydrochloride injection for tracing was used for preoperative localization under ultrasound guidance
Sponsors
Hunan Cancer Hospital
Eligibility
Sex/Gender
All
Age
18 Years to 70 Years
Inclusion criteria
Inclusion criteria: 1. Age of 18-70 years old (including 18 and 70 years old), male and female; 2. Preoperative clinical diagnosis of PTC, imaging examination (such as ultrasound, CT) suspected lateral cervical lymph node metastasis, after MDT discussion, lateral cervical lymph node dissection was planned; 3. No obvious contraindications to surgery were found in routine preoperative examination; 4. Be able to communicate well with researchers and complete research according to research regulations; 5. Patients voluntarily participated in this study and signed informed consent.
Exclusion criteria
Exclusion criteria: 1. Patients with hypersensitivity constitution, or history of severe drug allergy, or allergy to anthraquinone drugs; 2. History of drug abuse or substance abuse within the past year; 3. History of thyroid surgery, radioactive iodine therapy, or neck radiotherapy; 4. Hemoglobin (HB) 3 times the upper limit of normal (in patients with liver metastasis, ALT and AST >5 times the upper limit of normal); 6. Serum creatinine (Cr) >1.5 times the upper limit of normal; 7. Participation in other clinical trials within 3 months prior to this trial; 8. Patients with neurological disorders, psychiatric disorders, or intellectual disabilities who are unable to accurately describe their own symptoms; 9. Pregnant or lactating women; 10. Subjects and their spouses have plans for pregnancy during the trial period or within 6 months after the trial; 11. Researchers involved in this trial shall not participate as subjects; 12. Other subjects deemed unsuitable for participation by the investigator.
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| The identification rate and the number of lymph nodes dissected marked by lymphatic tracer;Evaluation of the diagnostic efficacy of preoperative auxiliary examination methods; | — |
Secondary
| Measure | Time frame |
|---|---|
| Postoperative recurrence rate;Postoperative complication rate;Surgical duration and extent of lymph node dissection; | — |
Countries
China
Contacts
Public ContactPeng Xiaowei
Hunan Cancer Hospital
Outcome results
None listed