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Evaluation of the therapeutic effect of PRP combined with sodium hyaluronate injection in the treatment of lumbar intervertebral disc protrusion complicated with sacroiliac joint disorder

The Efficacy of Platelet-Rich Plasma Combined with Sodium Hyaluronate Injection in the Treatment of Lumbar Disc Herniation with Sacroiliac Joint Dysfunction

Status
Active, not recruiting
Phases
Unknown
Study type
Interventional
Source
ChiCTR
Registry ID
ChiCTR2500113158
Enrollment
Unknown
Registered
2025-11-25
Start date
2025-12-01
Completion date
Unknown
Last updated
2025-12-01

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Lumbar Disc Herniation with Sacroiliac Joint Dysfunction Complicated by Lumbosacral Radiculopathy and Functional Impairment

Interventions

Experimental Group: Platelet-rich plasma (PRP) combined with sodium hyaluronate (HA) therapy.:Treatment with Platelet-Rich Plasma (PRP) combined with Sodium Hyaluronate (HA).
Control Group: Conventional radiofrequency ablation (RFA) therapy.:Standard RFA therapy

Sponsors

Songyang County Hospital of traditional Chinese Medicine
Lead Sponsor

Eligibility

Sex/Gender
All
Age
18 Years to 60 Years

Inclusion criteria

Inclusion criteria: 1.Meet the diagnostic criteria for LDH (lumbar disc herniation) combined with sacroiliac joint dysfunction. 2.Age between 18 and 60 years. 3.Able to complete the treatment according to the study plan. 4.Signed informed consent form;

Exclusion criteria

Exclusion criteria: 1.Pregnant or lactating women. 2.Patients with imaging evidence of lumbar vertebral bone destruction (e.g., tumors, tuberculosis, etc.). 3.Patients with comorbid conditions such as lumbar spondylolisthesis, osteoporosis, or spinal stenosis. 4.Patients with severe primary diseases, such as liver, kidney, heart, cerebrovascular, or hematopoietic system disorders. 5.Patients for whom the efficacy of previously received Chinese or Western medications for LDH combined with sacroiliac joint dysfunction cannot be determined, or those with incomplete data that may affect efficacy evaluation. 6.Patients unwilling to participate in the study or who voluntarily withdraw during the treatment process. 7.Patients receiving other concurrent treatments.

Design outcomes

Primary

MeasureTime frame
Visual Analog Scale (VAS) for pain intensity(VAS);Modified Japanese Orthopaedic Association (M-JOA) Score for Low Back Pain;Orlando Pelvic Outcome Score;Pelvic Deviation Value (PD Value);

Countries

China

Contacts

Public ContactQue Qihong

Songyang County Hospital of traditional Chinese Medicine

13906787146@163.com+86 578 8072216

Outcome results

None listed

Source: ChiCTR (via WHO ICTRP) · Data processed: Feb 4, 2026