Malignant tumors such as head and neck cancer, colorectal cancer, or pancreatic cancer that overexpresses NTSR1
Conditions
Interventions
Gold Standard:Serum-related tumor markers, ultrasound, CT, MRI imaging data, and histopathological examinations.
Index test:68Ga-FL-091 or 111In-FL-091 radionuclide imaging.
Sponsors
Union Hospital, Tongji Medical College, Huazhong University of Science and Technology
Eligibility
Sex/Gender
All
Age
18 Years to No maximum
Inclusion criteria
Inclusion criteria: 1.The subject or his legal representative was able to sign the informed consent form; 2.Commit to abide by research procedures and cooperate with the implementation of the full-process research; 3.Adult patient or healthy volunteer (age 18 years or above), male or female; 4.Patients with clinically suspected or confirmed malignant tumors such as head and neck cancer, colorectal cancer and pancreatic adenocarcinoma who is generally in good condition; 5.Pathological results to be obtained by biopsy or surgical resection;
Exclusion criteria
Exclusion criteria: 1.Patient or his legal representative is unable or unwilling to sign informed consent; 2.Failure to cooperate with the implementation of full-process research; 3.Acute systemic disease and electrolyte disorders; 4.pregnant or nursing women;
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| SUVmax;SUVmean;T/B ratio; | — |
Secondary
| Measure | Time frame |
|---|---|
| Electrocardiogram;Immunochemical staining of biopsy/surgical tissue sections;Biochemical indicators such as blood routine, urine routine, liver and kidney functions; | — |
Countries
China
Contacts
Public ContactXiaoli Lan
Union Hospital, Tongji Medical College, Huazhong University of Science and Technology
Outcome results
None listed