Acute Myocardial Infarction
Conditions
Interventions
Mindfulness-Based Stress Reduction (MBSR) group:Patients received standard post-PCI pharmacotherapy and an 8-week mindfulness-based stress reduction program.
Sponsors
The First Affiliated Hospital of Kunming Medical University
Eligibility
Sex/Gender
All
Age
18 Years to 70 Years
Inclusion criteria
Inclusion criteria: (1) Aged 18–70 years; (2) Diagnosed with ST-segment elevation myocardial infarction (STEMI) or non-ST-segment elevation myocardial infarction (NSTEMI) and successfully underwent emergency PCI within 24 hours of symptom onset; (3) Clinically stable at 1 month after PCI; (4) Completed high school education or above, with intact cognitive function (MMSE score >= 24); (5) Voluntarily participate and provide signed informed consent.
Exclusion criteria
Exclusion criteria: (1) Presence of severe comorbidities such as heart failure (NYHA class IV), end-stage renal disease, active malignancy, acute infection, or autoimmune diseases; (2) Use of immunosuppressive therapy within the past 3 months; (3) Previous participation in structured mind-body interventions; (4) Diagnosis of major psychiatric disorders or severe depression; (5) Any other conditions deemed unsuitable for participation by the investigators.
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| C-reactive protein;Interleukin-6;Procalcitonin;Left Ventricular Ejection Fraction;Global Longitudinal Strain;Motion Score Index;Genome-wide DNA Methylation Level; | — |
Secondary
| Measure | Time frame |
|---|---|
| Generalized Anxiety Disorder-7 (GAD-7) Score;Patient Health Questionnaire-9 (PHQ-9) Score; | — |
Countries
China
Contacts
Public ContactMin Zhang
The First Affiliatted Hospital of Kunming Medical University
Outcome results
None listed