Critically ill patients
Conditions
Interventions
BIS group:the BIS group received a conventional sedation-analgesia protocol.
control group:After the patients entered the ideal sedation depth, the patients in the control group received the routine analgesia and sedation scheme.
Sponsors
The Second Affiliated Hospital of Shantou University Medical College
Eligibility
Sex/Gender
All
Age
18 Years to 80 Years
Inclusion criteria
Inclusion criteria: 1. Patients who receive invasive mechanical ventilation therapy and sedation after admission to the ICU; 2. The duration of mechanical ventilation therapy combined with the use of analgesic and sedative drugs is = 48 hours; 3. Age <= 80 years old.
Exclusion criteria
Exclusion criteria: 1. Individuals who have had long-term alcoholism, drug use, or use of sedatives and sleeping pills before being admitted to the ICU; 2. Individuals with cranial lesions, neurological disorders, and mental abnormalities; 3. Cognitive function is limited; 4. Individuals allergic to sedatives; 5. People with limb movement disorders or neurological and muscular diseases.
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| The duration of ICU stay;The duration of mechanical ventilation;The dosage of propofol, average dosage of propofol per hour, total dosage of midazolam, and average dosage of midazolam per hour ; | — |
Secondary
| Measure | Time frame |
|---|---|
| Adverse reactions and events during sedation ; | — |
Countries
China
Contacts
Public ContactDanwei Cai
The Second Affiliated Hospital of Shantou University Medical College
Outcome results
None listed