Crohn's disease
Conditions
Interventions
Gold Standard:Diagnosing LMM in CD patients by calculating the psoas muscle index (PMI) through a CT scan at the level of the third lumbar vertebra (L3). According to the 2019 Asian Working Group for
females: PMI < 3.6 cm²/m² (ages 18–40) or < 3.3 cm²/m² (ages 41–60).
Index test:Body Composition Analysis (Bioelectrical Impedance Analysis, BIA)
Sponsors
Xiangya Hospital Central South University
Eligibility
Sex/Gender
All
Age
18 Years to 60 Years
Inclusion criteria
Inclusion criteria: (1) Patients diagnosed with CD according to the European Crohn's and Colitis Organization (ECCO) guidelines and aged >= 18 years; (2) Patients underwent both abdominal non-contrast computed tomography (CT) and bioelectrical impedance analysis (BIA) concurrently within 48 hours of admission.
Exclusion criteria
Exclusion criteria: (1) Baseline data missing rate >20%; (2) Presence of comorbid conditions that may cause sarcopenia (e.g., liver cirrhosis, hyperthyroidism, malignant tumors, severe infections, etc.); (3) Use of glucocorticoids or other medications that affect hydration status; (4) Pregnant or lactating women.
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| Low muscle mass;Accuracy; | — |
Secondary
| Measure | Time frame |
|---|---|
| Sensitivity;Specificity;Abdominal Computed Tomography; | — |
Countries
China
Contacts
Public ContactYu Peng
Xiangya Hospital, Central South University
Outcome results
None listed