Remifentanil-induced general anesthesia
Conditions
Interventions
Group OR:2mg oxelidine is configured to 5ml
Group SR:0.9% saline 5ml
Sponsors
The First People's Hospital of Tianshui
Eligibility
Sex/Gender
All
Age
18 Years to 70 Years
Inclusion criteria
Inclusion criteria: Patients aged 18-70 years with ASA physical status I-III scheduled for general anesthesia induction with remifentanil.
Exclusion criteria
Exclusion criteria: Patients were excluded due to conditions predisposing them to spontaneous cough, such as allergies, sinus bradycardia, severe neurological, respiratory, or cardiovascular diseases, dependence on anesthetics or a recent history of opioid use, smoking history, hepatic or renal dysfunction, biliary surgery, pregnancy, lactation, delivery surgery, or an upper respiratory tract infection within the two weeks preceding surgery.
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| Incidence of cough within 2 minutes following the start of remifentanil infusion.; | — |
Secondary
| Measure | Time frame |
|---|---|
| Number of patients with different degree of cough ;Systolic blood pressure;Diastolic blood pressure;Heart rate;Oxygen saturation;Other side effects related to the use of oliceridine and remifentanil were also recorded, including truncal rigidity, oxygen desaturation (SpO? < 90%) or apnea, as well as nausea and vomiting.; | — |
Countries
China
Contacts
Public ContactLi Chenguang
The First People's Hospital of Tianshui
Outcome results
None listed