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Transversus abdominis plane block in the study of postoperative PONV after laparoscopic cholecystectomy

Transversus abdominis plane block in the study of postoperative PONV after laparoscopic cholecystectomy

Status
Active, not recruiting
Phases
Unknown
Study type
Interventional
Source
ChiCTR
Registry ID
ChiCTR2500113033
Enrollment
Unknown
Registered
2025-11-24
Start date
2025-11-24
Completion date
Unknown
Last updated
2025-12-01

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

None listed

Interventions

Experimental Group (Group S):The patient underwent left and right TAP blocks preoperatively, with 15 ml of liposomal bupivacaine solution administered on each side.
Control group (Group C):The patient underwent bilateral serratus anterior block before surgery, with 15 ml of liposomal bupivacaine solution administered on each side.

Sponsors

The Second Affiliated Hospital of Chongqing Medical University
Lead Sponsor

Eligibility

Sex/Gender
All
Age
18 Years to 65 Years

Inclusion criteria

Inclusion criteria: 1) Planned laparoscopic cholecystectomy with postoperative analgesia not using PCIA 2) American Society of Anesthesiologists (ASA) physical status classification I–III 3) BMI 18.5-28.5 4) Age >=18 years and <65 years 5) Voluntary participation and able to understand and sign the informed consent form

Exclusion criteria

Exclusion criteria: 1) History of previous abdominal open surgery 2) Concurrent neuromuscular diseases leading to decreased abdominal muscle tone 3) Patients with cognitive impairment or difficulty communicating 4) Malignant tumors causing cachexia or massive ascites 5) Severe lesions in other systems (e.g., severe ventilatory dysfunction in COPD, cor pulmonale, multi-vessel coronary artery disease in patients with coronary heart disease, liver or kidney failure, etc.) 6) History of neurological disorders, such as stroke, traumatic brain injury, spinal cord injury, etc.

Design outcomes

Primary

MeasureTime frame
Postoperative vomiting incidence;Nausea NRS score;Proportion of internal oblique muscle thickening;

Secondary

MeasureTime frame
Pain Intensity (Visual Analog Scale, VAS);

Countries

China

Contacts

Public ContactDuan Guangyou

The Second Affiliated Hospital of Chongqing Medical University

duangy@hospital.cqmu.edu.cn+86 183 2337 6014

Outcome results

None listed

Source: ChiCTR (via WHO ICTRP) · Data processed: Feb 4, 2026