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Clinical and biomechanical study of high tibial osteotomy under different target force in the treatment of medial compartment osteoarthritis of the knee

Clinical and biomechanical study of high tibial osteotomy under different target force in the treatment of medial compartment osteoarthritis of the knee

Status
Recruiting
Phases
Unknown
Study type
Interventional
Source
ChiCTR
Registry ID
ChiCTR2500113009
Enrollment
Unknown
Registered
2025-11-24
Start date
2026-01-01
Completion date
Unknown
Last updated
2025-12-01

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Medial compartment osteoarthritis of the knee

Interventions

WBL50~55% group:Taking WBL50-55% as the ideal correction position of the tibial plateau, the lower limb force line was measured using the tibial high-level osteotomy software (APP HTO system, Osteo Ma
WBL55~60% group:Taking WBL55-60% as the ideal correction position of the tibial plateau, the lower limb force line was measured using the tibial high-level osteotomy software (APP HTO system, Osteo Ma
WBL6

Sponsors

Luoyang Orthopedic Hospital of Henan Province
Lead Sponsor

Eligibility

Sex/Gender
All
Age
40 Years to 65 Years

Inclusion criteria

Inclusion criteria: (1) Advanced stage of knee osteoarthritis (with genu varum deformity), the pain mainly concentrates on the medial side of the knee joint in osteoarthritis, and conservative treatment for more than half a year has been ineffective. The X-ray shows a Kellgren-Lawrence grade III patient; (2) The X-ray in the weight-bearing position shows narrowing of the medial gap, genu varum deformity, with an angle exceeding 5°, the lateral gap is basically normal, the knee joint structure is basically normal, and MRI indicates intact knee ligament function, knee joint stability, and no knee dislocation changes; (3) The knee joint flexion range of motion is > 90°, and the varus angle is = 18.5 kg/m².

Exclusion criteria

Exclusion criteria: (1) Those with injury to the cruciate ligament or collateral ligament of the knee; (2) Those with moderate to severe osteoarthritis in the patellofemoral compartment or lateral compartment; (3) Those with severe internal medical conditions and who, after assessment, cannot tolerate this surgery; (4) Those with wounds in the surgical area or active infections throughout the body; (5) Those with mental disorders or during pregnancy; (6) Those with severe osteoporosis; (7) Those with bone diseases caused by conditions such as gout, rheumatoid arthritis, ankylosing spondylitis, or tumors; (8) Those with neuropathic lesions around the knee joint; (9) Those who have undergone surgical treatment of the knee joint or have a history of joint cavity injections recently.

Design outcomes

Primary

MeasureTime frame
Western Ontario and McMaster Universities Osteoarthritis Index;Finite Element Analysis;

Secondary

MeasureTime frame
Visual Analogue Scale;Knee Society Score;Imaging Evaluation;

Countries

China

Contacts

Public ContactTan Honglue

Henan Luoyang Orthopedic Hospital (Henan Orthopedic Hospital)

hnlc.love@163.com+86 150 3635 8806

Outcome results

None listed

Source: ChiCTR (via WHO ICTRP) · Data processed: Feb 4, 2026