Patients undergoing lumbar spine surgery under general anesthesia who require a postoperative analgesia pump
Conditions
Interventions
Experimental group:Postoperative analgesia with Tegileridine
Sponsors
Shunde Hospital, Guangzhou University of Chinese Medicine
Eligibility
Sex/Gender
All
Age
18 Years to 75 Years
Inclusion criteria
Inclusion criteria: Aged 18–75 years; planned to undergo lumbar spine surgery; ASA classification I–III, with no severe liver or kidney dysfunction; no consciousness disorders, able to communicate normally with the physician, and clearly express personal needs.
Exclusion criteria
Exclusion criteria: Long-term use of opioid drugs (>3 months) or immunosuppressants; history of long-term use of psychotropic drugs or cognitive impairment; inability to communicate or presence of mental disorders; existing gastrointestinal dysfunction, or a history of abdominal surgery.
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| the time of the patient's first postoperative flatus; | — |
Secondary
| Measure | Time frame |
|---|---|
| Time of the patient's first postoperative bowel movement;Postoperative recovery time of bowel sounds in patients;The patient's first oral intake after surgery;The levels of gastrin in the patient's blood before surgery and one day after surgery;The content of substance P in the patient's blood before surgery and one day after surgery;The levels of vasoactive intestinal peptide in the patient's blood before surgery and one day after surgery;Disgusting;Vomiting;Abdominal bloating;Drowsiness;Respiratory depression;Itchy skin;Postoperative pain score;Postoperative opioid rescue dose;Number of venous pump compressions; | — |
Countries
China
Contacts
Public ContactHuayan Pan
Department of Anesthesiology, Shunde Hospital of Guangzhou University of Chinese Medicine
Outcome results
None listed