Cognitive dysfunction
Conditions
Interventions
SGB Group:Preoperative implementation of ultrasound-guided stellate ganglion block. For ultrasound-guided stellate ganglion block, a linear transducer with a frequency of 3–15 MHz is generally selecte
Control group:Patients in the control group received general anesthesia. Anesthesia was induced with 0.2 mg/kg of Cisatracurium Besylate for Injection [Manufacturer: Shangdong Dongying (Jiangsu) Pharm
Approval Number: National Drug Approval H20123332
Specification: 10 mg (based on C53H72N2O12)], 0.4 µg/kg of Sufentanil Citrate Injection [Manufacturer: Yichang Renfu Pharmaceutical Co., Ltd.
Approval Number: National Drug Approval H20054171
Specification: 1 mL: 50 µg (based on C22H30N2O2S)], and 2 mg/kg of Propofol Medium/Long-Chain Fat Emulsion Injection [Manufacturer: Guangdong Jiabo Pharmaceutical Co., Ltd.
Approval Number: Nat
Sponsors
The People's Hospital of Shihezi City, Xinjiang
Eligibility
Sex/Gender
All
Age
60 Years to 100 Years
Inclusion criteria
Inclusion criteria: 1 Age >= 60 years; 2 Confirmed by imaging to meet the standards for orthopedic surgery; 3 American Society of Anesthesiologists (ASA) classification of I–III; 4 No adverse reactions such as allergies to the drugs and medical devices used in this study.
Exclusion criteria
Exclusion criteria: 1 Combined organic diseases or presence of malignant tumors in the body; 2 Presence of lower extremity venous thrombosis ; 3 Coagulation dysfunction or immune deficiency; 4 Chronic diseases such as hypertension or diabetes; 5 Severe obesity or severe malnutrition; 6 Previous lower extremity injuries of varying degrees.
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| Adrenaline;Cortisol;C-reactive protein ;Interleukin-6;Visual Analogue Scale, VAS; | — |
Secondary
| Measure | Time frame |
|---|---|
| Heart rate;Blood pressure; | — |
Countries
China
Contacts
Public ContactWu Xiuling
The People's Hospital of Shihezi City, Xinjiang
Outcome results
None listed