Skip to content

Differential expression of serum proteins in stroke patients with concomitant respiratory failure based on serum proteomic analysis

Differential expression of serum proteins in stroke patients with concomitant respiratory failure based on serum proteomic analysis

Status
Recruiting
Phases
Unknown
Study type
Observational
Source
ChiCTR
Registry ID
ChiCTR2500112972
Enrollment
Unknown
Registered
2025-11-21
Start date
2024-07-18
Completion date
Unknown
Last updated
2025-11-24

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Prolonged disorders of consciousness

Interventions

Case group:None
Control group:None

Sponsors

Shenzhen Dapeng New District Nanao People's Hospital
Lead Sponsor

Eligibility

Sex/Gender
All
Age
18 Years to No maximum

Inclusion criteria

Inclusion criteria: Inclusion criteria for case groups: (1) Meet the diagnostic criteria of pDoC; (2) Age >=18 years old; (3) The course of consciousness disorder exceeds 28 days; (4) Complete blood collection; (5) Baseline data and imaging data are complete; (6) The patient or their family members sign the informed consent form. Inclusion criteria for the control group: (1) The initial admission diagnosis met the pDoC diagnostic criteria; (2) Consciousness recovery: The CRS-R score was adopted, with 6 points for movement or 2 points for communication. (3) Age >=18 years old; (4) The course of consciousness disorder exceeds 28 days; (5) Complete blood collection; (6) Baseline data and imaging data are complete; (7) The patient or their family members sign the informed consent form.

Exclusion criteria

Exclusion criteria: (1) Combined with other serious organic diseases: Patients with other serious organic diseases were excluded to ensure that the disease of the study object was single. (2) Incomplete clinical data: Stroke patients who could not be fully analyzed due to incomplete clinical data were excluded. (3) Unqualified serum samples: Excluded samples with unqualified serum samples or unable to meet the requirements of the experiment.

Design outcomes

Primary

MeasureTime frame
Protein;

Countries

China

Contacts

Public ContactChen Yuan

Shenzhen Dapeng New District Nanao People's Hospital

15989816939@163.com+86 755 8440 0309

Outcome results

None listed

Source: ChiCTR (via WHO ICTRP) · Data processed: Feb 4, 2026