Chronic Kidney Diseases
Conditions
Interventions
the finerenone group:NA
Sponsors
Provincial Hospital Affiliated to Fuzhou University
Eligibility
Sex/Gender
All
Age
18 Years to 80 Years
Inclusion criteria
Inclusion criteria: 1. Stable patients who have been on continuous ambulatory peritoneal dialysis (CAPD) in the Department of Nephrology of our hospital for more than 3 months and attend for routine CAPD assessment. 2. Aged 18–80 years. 3. Concomitant treatment with an ARB or ACEI for > 3 months. 4. Use of neutral-pH dialysis solution and/or icodextrin-based dialysate.
Exclusion criteria
Exclusion criteria: 1. Hyperkalemia (K? > 5 mmol/L) 2. Anemia (Hb < 9.0 g/dL) 3. NYHA Class III or IV heart failure 4. Use of acidic-pH dialysis fluid 5. Previous hemodialysis or kidney transplantation within the past 3 years, pregnancy or suspected pregnancy 6. Hepatic impairment, cholestasis, or biliary cirrhosis 7. Peritonitis or any severe systemic infection 8. Conditions that may interfere with follow-up, e.g., malignancy, drug or alcohol abuse 9. Severe psychiatric disorder
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| plasma-Finerenone; | — |
Secondary
| Measure | Time frame |
|---|---|
| urine-Finerenone;peritoneal dialysis fluid-Finerenone; | — |
Countries
China
Contacts
Public ContactLin Miao
Provincial Hospital Affiliated to Fuzhou University
Outcome results
None listed