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Analysis and Predictive Model of Multidimensional Risk Factors for Early Neurological Deterioration in Large Vessel Occlusion with Mild Stroke

Analysis and Predictive Model of Multidimensional Risk Factors for Early Neurological Deterioration in Large Vessel Occlusion with Mild Stroke

Status
Active, not recruiting
Phases
Early Phase 1
Study type
Observational
Source
ChiCTR
Registry ID
ChiCTR2500112967
Enrollment
Unknown
Registered
2025-11-21
Start date
2026-01-01
Completion date
Unknown
Last updated
2025-11-24

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Acute ischemic stroke

Interventions

Observation group:NA

Sponsors

Hubei University of Medicine Affiliated People's Hospital
Lead Sponsor

Eligibility

Sex/Gender
All
Age
18 Years to 80 Years

Inclusion criteria

Inclusion criteria: 1. Age >= 18 years. 2. Acute ischemic stroke, NIHSS score upon admission <= 5 points. 3. CTA/MRA confirmed occlusion of major vessels in the anterior or posterior circulation (ICA, M1, proximal M2, basilar artery). 4. Time from onset to admission < 24 hours. 5. Clinical data is complete and accessible.

Exclusion criteria

Exclusion criteria: 1. Non-atherosclerotic causes (such as dissection, moyamoya disease, vasculitis). 2. mRS score before stroke > 2 points (existing severe disability). 3. Accompanied by other severe intracranial diseases (such as tumors, infections) that interfere with assessment. 4. Presence of absolute contraindications to intravascular therapy or standard drug treatment. 5. Key data missing (e.g., baseline NIHSS, follow-up imaging, or 90-day mRS).

Design outcomes

Primary

MeasureTime frame
the incidengce of Early neurological deterioration;

Secondary

MeasureTime frame
NIHSS;Vessel occlusion location;Length of thrombus;Treatment method;3-month functional outcomes;

Countries

China

Contacts

Public ContactMeng Shuqing

Hubei University of Medicine Affiliated People's Hospital

251204492@qq.com+86 137 3354 9210

Outcome results

None listed

Source: ChiCTR (via WHO ICTRP) · Data processed: Feb 4, 2026