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Liposomal Bupivacaine Injection Provides Adequate Postoperative Analgesia for Third Molar Extraction: A Prospective Cohort Study

Liposomal Bupivacaine Injection Provides Adequate Postoperative Analgesia for Third Molar Extraction: A Prospective Cohort Study

Status
Active, not recruiting
Phases
Unknown
Study type
Interventional
Source
ChiCTR
Registry ID
ChiCTR2500112940
Enrollment
Unknown
Registered
2025-11-21
Start date
2025-11-28
Completion date
Unknown
Last updated
2025-11-24

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

None

Interventions

MGroup(Male):Postoperative pain was managed with local infiltration anesthesia using liposomal bupivacaine
FGroup(Female):Postoperative pain was managed with local infiltration anesthesia using liposomal bupivacaine

Sponsors

Stomatological Hospital Affiliated to Chongqing Medical University
Lead Sponsor

Eligibility

Sex/Gender
All
Age
18 Years to 60 Years

Inclusion criteria

Inclusion criteria: 1. Adults aged 18 to 60 2. Undergoing extraction of the third molar on one side of the mandible. For impacted third molars, the lowest point of the tooth occlusal surface is lower than the cervical region of the adjacent second molar, or the teeth are completely buried within the bone. 3. Physical condition of the American Society of Anesthesiologists (ASA) is I to II 4. Willing to cooperate with the postoperative analgesia score assessment

Exclusion criteria

Exclusion criteria: 1. Without informed consent 2. Allergy to bupivacaine 3. Chronic pain or preoperative use of analgesic medications 4. Renal or hepatic dysfunction 5. Psychiatric disorders or inability to cooperate with assessment 6. Menstrual period in female patients

Design outcomes

Primary

MeasureTime frame
Dose of liposomal bupivacaine ED95;Pain score;

Secondary

MeasureTime frame
Numbness score;Complications;Pain Ratio;The modified dental anxiety scale;

Countries

China

Contacts

Public ContactNan Zhao

Stomatological Hospital Affiliated to Chongqing Medical University

500158@hospital.cqmu.edu.cn+86 185 2312 9117

Outcome results

None listed

Source: ChiCTR (via WHO ICTRP) · Data processed: Feb 4, 2026