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Fecal Sample-Based Individualized Eradication Therapy for Helicobacter pylori Infection in Treatment-Naïve Patients

A Clinical Study of Fecal Sample-Based Individualized Eradication Therapy in Treatment-Naïve Patients With Helicobacter pylori Infection: Multicenter randomized controlled trial

Status
Active, not recruiting
Phases
Unknown
Study type
Interventional
Source
ChiCTR
Registry ID
ChiCTR2500112936
Enrollment
Unknown
Registered
2025-11-21
Start date
2025-11-24
Completion date
Unknown
Last updated
2025-11-24

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Helicobacter pylori (H.pylori) infection

Interventions

Empirical Eradication Therapy Group:Dual regimen
Individualized Eradication Therapy Group:Individualized Eradication Therapy Regimens

Sponsors

Peking University Third Hospital
Lead Sponsor

Eligibility

Sex/Gender
All
Age
18 Years to 75 Years

Inclusion criteria

Inclusion criteria: 1. Patients who visit our center due to current Hp infection; 2. Have not undergone eradication therapy; 3. Aged 18-75 years; 4. Both male and female, willing to participate and able to cooperate with this study.

Exclusion criteria

Exclusion criteria: 1. Individuals who have previously undergone H. pylori eradication treatment; 2. Use of medications within 4 weeks prior to enrollment that may affect the study results, such as proton pump inhibitors (PPIs), potassium-competitive acid blockers (P-CABs), bismuth agents, antibiotics, etc.; 3. Patients with gastrointestinal malignancies; 4. Patients who have undergone gastrointestinal surgery; 5. Individuals with significant diseases of the heart, lungs, kidneys, liver, blood, nervous system, endocrine system, or mental health; 6. Those allergic to the medications used in this study; 7. Pregnant or breastfeeding women; 8. Individuals with alcohol abuse; 9. Patients with other medical conditions that may increase treatment-related adverse reactions; 10. Individuals unable to cooperate with this study.

Design outcomes

Primary

MeasureTime frame
Eradication rate;

Secondary

MeasureTime frame
Safety (incidence of adverse reactions);Compliance;

Countries

China

Contacts

Public ContactZhou Liya

Peking University Third Hospital

zhoumed@126.com+86 10 82264601

Outcome results

None listed

Source: ChiCTR (via WHO ICTRP) · Data processed: Feb 4, 2026