insomnia
Conditions
Interventions
Group without insomnia in coronary heart disease:Na
Group with insomnia in coronary heart disease:Insomnia
Sponsors
Guabgzhou First People‘s Hospital
Eligibility
Sex/Gender
All
Age
50 Years to 70 Years
Inclusion criteria
Inclusion criteria: 1. Gender is not limited, age 50-70 years old. 2. Patients in the coronary heart disease group must have a clear diagnosis of coronary atherosclerotic heart disease, including previous myocardial infarction, confirmed by coronary angiography or evidence of percutaneous coronary intervention (PCI)/bypass surgery, and the condition must be stable (no active acute coronary syndrome). 3. Patients in the coronary heart disease with insomnia group must meet the clinical diagnostic criteria for insomnia (such as the International Classification of Sleep Disorders, 3rd Edition (ICSD-3) or the Diagnostic and Statistical Manual of Mental Disorders, 5th Edition (DSM-5) criteria for insomnia disorder). 4. All subjects must provide informed consent and voluntarily participate in the study. Coronary heart disease patients must have good compliance and be willing to cooperate in completing questionnaires and imaging examinations.
Exclusion criteria
Exclusion criteria: 1. Patients with other conditions that may significantly affect sleep or cardiovascular function are excluded. 2. Patients who have used drugs that may affect the central nervous system within the last three months are excluded, including excessive use of benzodiazepine hypnotics and the adjustment period of antidepressants. 3. Patients with contraindications for magnetic resonance imaging (MRI) are excluded. 4. Patients with other serious physical diseases are excluded.
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| Heart Rate Variability (HRV)?;Insomnia Severity (Pittsburgh Sleep Quality Index (PSQI) Score and Insomnia Severity Index (ISI)Score)?;fMRI-based Functional Brain Connectivity??; | — |
Countries
China
Contacts
Public ContactYanlu Ying
Guabgzhou First People‘s Hospital
Outcome results
None listed