Diabetic macrovascular complications
Conditions
Interventions
Sponsors
Affiliated Qidong Hospital of Nantong University/Qidong People’s Hospital
Eligibility
Sex/Gender
All
Age
18 Years to 80 Years
Inclusion criteria
Inclusion criteria: 1.Type 2 diabetes patients meeting the WHO 1999 diagnostic criteria for diabetes;2.Participants engaged in MMC management for =3 years with complete medical records (including but not limited to glycemic, lipid, and blood pressure profiles).
Exclusion criteria
Exclusion criteria: 1. Patients with type 1 diabetes or specific types of diabetes; 2. Patients with incomplete or missing critical data (e.g., lack of key follow-up records or primary endpoint data); 3. Comorbid severe systemic diseases: including end-stage renal disease (ESRD), liver cirrhosis, atrial fibrillation, or other conditions significantly affecting prognosis; 4. Pre-existing severe macrovascular complications (e.g., myocardial infarction, massive stroke, or peripheral arterial occlusion diagnosed at baseline); 5. Hypercoagulable states secondary to hematologic disorders: antiphospholipid syndrome, inherited coagulation disorders, multiple myeloma, polycythemia vera, etc.; 6. Special physiological status: pregnancy or lactation; 7. Autoimmune diseases: systemic lupus erythematosus (SLE), rheumatoid arthritis, or vasculitis of other etiologies; 8. Active malignancies; 9. Psychiatric disorders compromising self-care capacity, cognitive impairment, or inability to comply with the protocol; 10. Uncontrolled hyperthyroidism or other endocrine disorders.
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| Ultrasonographic findings of carotid and major extremity arteries;Ankle-brachial index (ABI);Brachial-ankle pulse wave velocity (baPWV);Head CT/MRI;Coronary CTA; | — |
Secondary
| Measure | Time frame |
|---|---|
| Glycated hemoglobin (HbA1c);Blood pressure;Blood lipids;Body mass index (BMI);Waist-to-Hip (WHR); | — |
Countries
China
Contacts
Public ContactLi Xiaofeng
Affiliated Qidong Hospital of Nantong University/Qidong People’s Hospital
Outcome results
None listed