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Diagnostic value of combined detection of pepsinogen, gastrin-17, and 13C-urea breath test in children with chronic gastritis: A multivariate analysis

Diagnostic value of combined detection of pepsinogen, gastrin-17, and 13C-urea breath test in children with chronic gastritis: A multivariate analysis

Status
Active, not recruiting
Phases
Unknown
Study type
Observational
Source
ChiCTR
Registry ID
ChiCTR2500112900
Enrollment
Unknown
Registered
2025-11-20
Start date
2018-01-23
Completion date
Unknown
Last updated
2025-11-24

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Chronic gastritis

Interventions

Gold Standard:Painless Gastroscopy / Painless Gastroscopy with Gastric Mucosal Biopsy.
Index test:Measurement of serum pepsinogen (PG I/II) and gastrin-17 (G-17) by ELISA, the 13C-urea breath test (13C-UBT), and the combined detection of PG I/II, G-17, and 13C-UBT.

Sponsors

Shunde District Integrated Traditional Chinese and Western Medicine Hospital of Foshan City (Shunde District Jun'an Hospital of Foshan City)??
Lead Sponsor

Eligibility

Sex/Gender
All
Age
6 Years to 12 Years

Inclusion criteria

Inclusion criteria: 1.Participants in the healthy control group exhibited no gastrointestinal symptoms prior to physical examination; 2.Patients in the experimental group presented with gastrointestinal symptoms and were definitively diagnosed with chronic gastritis via gastroscopy or therapeutic intervention; 3.All participants had no contraindications to the examinations performed; 4.Patients were mentally clear, demonstrated good compliance, and voluntarily participated in the. study

Exclusion criteria

Exclusion criteria: 1.Individuals with severe cardiac, hepatic, or renal diseases; 2.Patients complicated with malignant tumors; 3.Those who had taken acid-suppressive or antimicrobial medications prior to the examination; 4.Subjects with coagulation disorders; 5.Patients suffering from psychiatric disorders that preclude cooperation.

Design outcomes

Primary

MeasureTime frame
Serum pepsinogen I/II;Gastrin-17;13C-urea breath test result;

Secondary

MeasureTime frame
Painless Gastroscopy and Biopsy;

Countries

China

Contacts

Public ContactGao Yiyun

Shunde District Integrated Traditional Chinese and Western Medicine Hospital of Foshan City (Shunde District Jun'an Hospital of Foshan City)??

golrialzz@163.com+86 137 2635 4055

Outcome results

None listed

Source: ChiCTR (via WHO ICTRP) · Data processed: Feb 4, 2026