Open injury of the finger
Conditions
Interventions
Experimental group:A mixture of liposomal bupivacaine injection (13.3 mg/mL) and bupivacaine hydrochloride (with a milligram dose ratio of 2:1 between liposomal bupivacaine injection and bupivacaine h
Control Group:A 1% lidocaine hydrochloride injection is used for digital nerve block.
Sponsors
Shanghai Sixth People's Hospital
Eligibility
Sex/Gender
All
Age
18 Years to No maximum
Inclusion criteria
Inclusion criteria: 1. Age 18 or above, regardless of gender; 2. Patients with open finger injuries requiring emergency surgical repair under digital nerve block anesthesia; 3. Voluntary signing of informed consent; 4. Ability and willingness to participate in follow-up via text message or phone call.
Exclusion criteria
Exclusion criteria: 1. Patients with a history of toxic reactions to local anesthesia; 2. Patients allergic to lidocaine or bupivacaine; 3. Patients with a history of drug abuse (anesthetics or alcohol) within the past 3 months; 4. Patients with chronic pain conditions (pain lasting more than 3 months); 5. Patients requiring emergency surgery on other parts of the hand besides the finger, where digital nerve block cannot meet anesthesia requirements; 6. Patients with contraindications for digital nerve block, such as tumors or local infections at the puncture site; 7. Patients with unstable systemic conditions, severe liver or kidney dysfunction, or coagulation disorders that preclude emergency surgery; 8. Patients with multiple systemic injuries; 9. Patients with psychiatric disorders; 10. Pregnant or breastfeeding women, or those with recent pregnancy plans; 11. Patients who refuse to participate in this clinical trial.
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| Visual Analog Scale (VAS) score at 2 days postoperatively;Changes from baseline of in ISI, PSQI, and EQ-VAS scores at 14 days postoperatively;Sleep quality within 14 days after surgery: Total sleep time, sleep latency, sleep efficiency, number of awakenings during the night, and sleep quality score within 14 days postoperatively.; | — |
Secondary
| Measure | Time frame |
|---|---|
| The amount of analgesic medication used within 14 days postoperatively. This includes the total dose of celecoxib capsules, the time of the first dose, and the duration of continuous use; as well as the MME (Morphine Milligram Equivalent) of opioid medications taken.;Onset time of anesthesia and duration of anesthesia;Visual Analog Scale (VAS) scores at 1, 3, 7, and 14 days postoperatively; | — |
Countries
China
Contacts
Public ContactYun Qian
Shanghai Sixth People‘s Hospital
Outcome results
None listed