Meibomian gland dysfunction
Conditions
Interventions
Sponsors
Eye Hospital, Wenzhou Medical University
Eligibility
Sex/Gender
All
Age
18 Years to No maximum
Inclusion criteria
Inclusion criteria: 1. The subjects included in this study were patients who visited our hospital from January 2021 to December 2023 and were diagnosed with meibomian gland dysfunction (MGD). The diagnostic criteria are as follows: (1) Dry eye diagnosis is based on the 2020 Chinese Consensus on Dry Eye Experts: 1) Patients report at least one subjective symptom such as eye dryness, foreign body sensation, burning sensation, fatigue, discomfort, redness, or fluctuating vision; Chinese Dry Eye Questionnaire score >=7 or OSDI >=13; and the patient has FBUT =75 or OSDI >=13, and FBUT >5s but 5mm/5min but =5 points. (2) Diagnosis of meibomian gland dysfunction is based on the 2017 Chinese Expert Consensus on Diagnosis and Treatment of MGD: 1) Abnormal eyelid margin or meibomian gland orifices; 2) Abnormal meibum secretion; 3) Presence of ocular symptoms; 4) Meibomian gland loss; 5) Abnormal lipid layer thickness. The presence of any one of items 1) or 2), combined with ocular symptoms in item 3), allows for a diagnosis of symptomatic MGD.
Exclusion criteria
Exclusion criteria: 1. Patients with severe dry eye requiring surgical treatment; 2. Those who have undergone eyelid surgery within 6 months prior to screening; 3. Patients who have received permanent punctal plug treatment or temporary punctal plug treatment within 6 months prior to screening; 4. Surgery-induced dry eye; 5. Patients with glaucoma; 6. Active systemic or ocular infections; 7. Patients with recurrent viral keratitis; 8. Patients with concomitant ocular cicatricial pemphigoid, significant conjunctival scarring, ocular chemical burns, neurotrophic keratoconjunctivitis, or post-eyelid tumor excision.
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| Ocular Surface Disease Index Score; | — |
Countries
China
Contacts
Public ContactLi Siyan
Eye Hospital, Wenzhou Medical University
Outcome results
None listed