Postanesthetic Complications
Conditions
Interventions
Group D: Dexmedetomidine Combined with Lidocaine (DexLido):Participants in Group D received a combined solution of 1 mL of 2% lidocaine (20 mg) and 1 mL of dexmedetomidine. The dose of dexmedetomidine
Group L: Lidocaine (Lido):Participants in Group L received 2 mL of 2% lidocaine (40 mg). Under video laryngoscopy guidance, the solution was administered via a calibrated spray catheter positioned 1 c
Group C: Normal Saline (Control):Participants in Group C (Control) received 2 mL of normal saline. Under video laryngoscopy guidance, the solution was administered via a calibrated spray catheter posi
Sponsors
The First People's Hospital of Neijiang
Eligibility
Sex/Gender
All
Age
3 Years to 12 Years
Inclusion criteria
Inclusion criteria: 1.Age: 3 to 12 years old (inclusive); 2.ASA Status: American Society of Anesthesiologists (ASA) Physical Status Class I or II; 3.Informed Consent: The child's parent or legal guardian has agreed to the trial procedure and provided written informed consent; 4.Child Assent: Children aged >=7 years old must voluntarily provide their own written assent.
Exclusion criteria
Exclusion criteria: 1.Scheduled surgical duration exceeding 80 minutes; 2.Known hypersensitivity to amide-type local anesthetics or dexmedetomidine; 3.Anticipated difficult airway requiring management with a laryngeal mask airway (LMA) or awake fiberoptic intubation; 4.History of congenital or idiopathic methemoglobinemia, or current use of any medications associated with methemoglobinemia; 5.Pre-existing chronic pharyngitis, or a history of tonsillectomy and/or adenoidectomy; 6.Presence of asthma, recent respiratory tract infection, chronic cough, or requirement for a repeat surgical procedure; 7.Significant cardiovascular disease.
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| The incidence of cough at extubation; | — |
Secondary
| Measure | Time frame |
|---|---|
| The severity of the cough at extubation;The incidence of laryngospasm;The incidence of postoperative sore throat;The incidence of postoperative hoarseness;Pediatric Anesthesia Emergence Delirium (PAED) scale score;Length of stay in the PACU;The incidence of cough at 24 hours postoperatively;Parental satisfaction score at 24 hours postoperatively; | — |
Countries
China
Contacts
Public ContactYihua Wang
The First People's Hospital of Neijiang
Outcome results
None listed