Acute lymphoblastic leukemia
Conditions
Interventions
Non-injury group (control group):None
Injury group (observation group):None
Sponsors
Shenzhen Children’s Hospital
Eligibility
Sex/Gender
All
Age
No minimum to 18 Years
Inclusion criteria
Inclusion criteria: 1.The child was diagnosed with acute lymphoblastic leukemia; 2.The treatment plan and risk grouping criteria were based on CCCG-ALL-2020 Childhood acute lymphoblastic leukemia treatment protocol; 3.Their age ranged from 1 month to 18 years; 4.All patients were newly diagnosed; 5.Liver function tests were normal before chemotherapy; 6.Patients have good compliance and can complete liver function tests regularly;
Exclusion criteria
Exclusion criteria: 1.Mature B-ALL, mixed leukemia; 2.Combined with other tumors; 3.Combined with autoimmune diseases; 4.??Patients who had undergone bone marrow transplantation; 5.Combined with underlying liver diseases, viral hepatitis and other liver diseases or diseases affecting liver function; 6.Patients who were unable to complete chemotherapy; 7.Children with incomplete diagnosis and treatment data;
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| ALT;AST;GGT;ALP; | — |
Secondary
| Measure | Time frame |
|---|---|
| IBIL;PT;ALB;TBA;TBIL;PA;INR;TP;DBIL; | — |
Countries
China
Contacts
Public Contactxuejuanli
Shenzhen Children’s Hospital
Outcome results
None listed