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Prospective real-world study of IVF/ICSI outcomes in poor responders with rLH addition

Prospective real-world study of IVF/ICSI outcomes in poor responders with rLH addition

Status
Recruiting
Phases
Unknown
Study type
Interventional
Source
ChiCTR
Registry ID
ChiCTR2500112821
Enrollment
Unknown
Registered
2025-11-19
Start date
2024-05-20
Completion date
Unknown
Last updated
2025-11-24

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Female infertility

Interventions

rLH:Rfsh150-300 IU, SC, qd
rLH 75-150IU, SC, qd. B-ultrasound and serum E2, LH, and P monitoring were performed every 1-4 days to adjust the dose of rFSH. The dose of rLH up to trigger day was maintained
control:Rfsh150-300 IU, SC, qd
B-ultrasound and serum E2, LH, and P monitoring were performed every 1-4 days to adjust the dose of rFSH. The dose of rLH up to trigger day was maintained

Sponsors

Reproductive medicine center of Tongji Hospital Affiliated to Tongji Medical College of Huazhong University of science and technology
Lead Sponsor

Eligibility

Sex/Gender
Female
Age
35 Years to 42 Years

Inclusion criteria

Inclusion criteria: 1.Age>=35 years old and =2700IU; 4. Patients undergoing IVF/ICSI using antagonist protocol.

Exclusion criteria

Exclusion criteria: 1. AMH3cm, reproductive system malformation; 3.Recurrent implantation failure and recurrent abortion; 4.Patients undergoing PGT; 5. Hypertension, diabetes and other underlying diseases; 6.Infertility caused by severe male factors, such as severe oligoasthenospermia or azoospermia.

Design outcomes

Primary

MeasureTime frame
Number of high-quality embryos in D3;

Secondary

MeasureTime frame
Number of oocytes retrieved;2PN fertilization rate;Clinical pregnancy rate;Live birth rate;Rate of abortion;

Countries

China

Contacts

Public ContactZheng Yu

Reproductive medicine center of Tongji Hospital Affiliated to Tongji Medical College of Huazhong University of science and technology

5914469@qq.com+86 134 3728 5515

Outcome results

None listed

Source: ChiCTR (via WHO ICTRP) · Data processed: Feb 4, 2026