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Bidirectional cohort study of ovarian dysfunction and reproductive outcomes

Bidirectional cohort study of ovarian dysfunction and reproductive outcomes

Status
Active, not recruiting
Phases
Unknown
Study type
Observational
Source
ChiCTR
Registry ID
ChiCTR2500112811
Enrollment
Unknown
Registered
2025-11-19
Start date
2025-12-01
Completion date
Unknown
Last updated
2025-11-24

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

decreased ovarian function

Interventions

Case group:None

Sponsors

Department of Reproductive Medicine, General Hospital of Eastern Theater Command, People's Liberation Army
Lead Sponsor

Eligibility

Sex/Gender
Female
Age
20 Years to 40 Years

Inclusion criteria

Inclusion criteria: Adopting the criteria from the 2022 Clinical Diagnosis and Treatment Expert Consensus on Declining Ovarian Reserve Function: Anti-Müllerian hormone < 1.1 ng/mL or antral follicle count < 5–7. (1) Meets criteria for ovarian reserve decline; (2) Female, aged 20 years <=age < 40 years; (3) Voluntarily participates in the trial and signs an informed consent form.

Exclusion criteria

Exclusion criteria: 1. Either partner suffers from severe mental illness, acute infections of the genitourinary system, or sexually transmitted diseases. 2. Suffering from genetic disorders specified in the Maternal and Child Health Care Law as unsuitable for childbearing, for which preimplantation genetic diagnosis is currently unavailable. 3. Either partner has serious harmful habits such as drug addiction. 4. Either party has been exposed to teratogenic levels of radiation, toxins, or pharmaceuticals and remains within the active period of such exposure. 5. The female partner possesses a uterus incapable of supporting pregnancy or suffers from severe physical conditions rendering pregnancy untenable.

Design outcomes

Primary

MeasureTime frame
pregnancy outcome ;Endocrine indicators;Ovulation-stimulating related indicators;

Countries

China

Contacts

Public ContactYaobing

General Hospital of Eastern Theater Command of the People's Liberation Army

yaobing@nju.edc.cn+86 138 1585 3296

Outcome results

None listed

Source: ChiCTR (via WHO ICTRP) · Data processed: Feb 4, 2026