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Comparison of the effect of different intravenous doses of dexmedetomidine in preventing shivering in cesarean section patients under spinal anesthesia: A clinical randomized controlled trial

Comparison of the Effects of Different Intravenous Doses of Dexamethasone on Preventing Shivering in Cesarean Section Patients under Spinal Anesthesia

Status
Recruiting
Phases
Early Phase 1
Study type
Interventional
Source
ChiCTR
Registry ID
ChiCTR2500112804
Enrollment
Unknown
Registered
2025-11-19
Start date
2025-11-20
Completion date
Unknown
Last updated
2025-11-24

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Comparison of the effects of anesthetics on maternal shivering

Interventions

Group A:Dexmedetomidine 0µg/kg
Group B:Dexmedetomidine 0.25µg/kg
Group C:Dexmedetomidine 0.50µg/kg
Group D:Dexmedetomidine 0.75µg/kg

Sponsors

The Second Affiliated Hospital of Guangdong Medical University
Lead Sponsor

Eligibility

Sex/Gender
Female
Age
22 Years to 50 Years

Inclusion criteria

Inclusion criteria: 1. Full-term pregnant women undergoing cesarean section at this hospital from August 1, 2024, to March 31, 2025. 2. Patients agree to undergo cesarean section and spinal anesthesia, and have signed the informed consent form. 3. Pregnant women classified as ASA I-II.

Exclusion criteria

Exclusion criteria: 1. Pregnant women with ASA classification III-IV; 2. Pregnant women with fever, temperature = or > 38°C; 3. Preterm pregnant women, less than 36 weeks; 4. Pregnant women planning to undergo cesarean section with complications such as placenta previa, placental abruption, severe preeclampsia or eclampsia, HIV positive, fetal malformations, fetal distress, etc. 5. Severe mental and neurological disorders; 6. Refusal to sign the informed consent form.

Design outcomes

Primary

MeasureTime frame
Time of chills;Grading of chills;

Secondary

MeasureTime frame
Vital signs;Sedation Score;Proportion of chills requiring Demerol treatment;

Countries

China

Contacts

Public ContactZeng Caihua

The Second Affiliated Hospital of Guangdong Medical University

jinxiaogao@yeah.net+86 139 0252 1985

Outcome results

None listed

Source: ChiCTR (via WHO ICTRP) · Data processed: Feb 4, 2026