Herpes Zoster Neuralgia
Conditions
Interventions
SCS Group:Perform spinal cord stimulation implantation (SCS)
Combined treatment group:Spinal cord stimulation combined with platelet-rich plasma injection
Sponsors
Jiangyou People's Hospital
Eligibility
Sex/Gender
All
Age
50 Years to 85 Years
Inclusion criteria
Inclusion criteria: 1. Age: 50 to 85 years old, gender not limited. 2. Consistent with the diagnosis of herpes zoster neuralgia (ZRN), the course of the disease is less than 3 months. 3. The Visual Analogue Scale (VAS) for pain at admission was >=4 points. 4. Voluntarily sign the informed consent form and be able to cooperate with the follow-up plan.
Exclusion criteria
Exclusion criteria: 1. Immunosuppressive status: Currently undergoing chemotherapy, biological agents, long-term glucocorticoids (>2 weeks), organ transplantation, or HIV positive. 2. Hematological abnormalities: Platelet count 1.5, or anticoagulant drugs are currently in use and cannot be discontinued. 3. Contraindications for puncture: Local skin infection, coagulation dysfunction, severe spinal deformity, or implantation of metal/pacemaker in the body that hinders SCS operation. 4. Coexisting with other chronic pain diseases (such as diabetic peripheral neuropathy, trigeminal neuralgia) may affect the evaluation of therapeutic efficacy. 5. Pregnancy, lactation or planning to become pregnant within 6 months. 6. Mental or cognitive impairment, unable to complete the scale assessment. 7. It is expected that the 3-month follow-up cannot be completed (severe comorbidities or life expectancy <3 months).
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| Pain score; | — |
Secondary
| Measure | Time frame |
|---|---|
| Quality of life;Sleep quality;Depression score;Inflammatory indicators;Dosage of analgesic drugs; | — |
Countries
China
Contacts
Public ContactGuangyang Zhu
Jiangyou People's Hospital
Outcome results
None listed