Perioperative anxiety and sleep disorders in hip and knee arthroscopic surgeries
Conditions
Interventions
experimental group:Preoperative routine anxiety reduction intervention + nasal spray of dexmedetomidine (100 µg per dose) group
control group:Preoperative routine anxiety reduction intervention + nasal spray of normal saline group
Sponsors
West China Hospital, Sichuan University
Eligibility
Sex/Gender
All
Age
18 Years to 65 Years
Inclusion criteria
Inclusion criteria: 1. Patients aged between 18 and 50 years old who are scheduled for elective surgeries; 2. Intending to undergo hip arthroscopy or knee arthroscopy; 3. ASA classification I-II; 4. Having a certain degree of preoperative anxiety (preoperative STAI-S score >= 40 points); 5. The surgery is planned to be performed under general anesthesia; 6. Agreeing to receive nasal spray intervention, and having no drug contraindications; 7. Signing the informed consent form, understanding the research purpose and process, and willing to follow the research protocol and follow-up arrangements.
Exclusion criteria
Exclusion criteria: 1. Those who are allergic to dexmedetomidine or its excipient components; 2. Those with significant nasal diseases or nasal obstruction (such as nasal polyps, severe nasal septum deviation, chronic rhinitis, etc.) that affect drug absorption; 3. Those with moderate to severe cardiovascular diseases (such as second-degree or higher atrioventricular block, bradycardia < 50 bpm, uncontrolled hypertension or hypotension); 4. Those with severe liver or kidney dysfunction; 5. Those with active mental disorders, severe depression or receiving psychiatric medication treatment; 6. Those with diagnosed sleep disorders or undergoing intervention (such as using melatonin, sedative-hypnotic drugs); 7. Those who used drugs that may affect anxiety levels within 7 days before the surgery (such as benzodiazepines, antidepressants, etc.); 8. Those who cannot cooperate in filling out the scale or undergoing postoperative follow-up (such as having language disorders, difficulty in reading, etc.); 9. Those with a history of hip and knee arthroscopy or other major joint surgeries in the past, which may affect the psychological baseline state.
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| State-Trait Anxiety Inventory,STAI-Form Y; | — |
Secondary
| Measure | Time frame |
|---|---|
| Amsterdam preoperative anxiety and information scale,APAIS;Generalized Anxiety Disorder,GAD-7;Pittsburgh Sleep Quality Index,PSQI;Leeds Sleep Evaluation Questionnaire,LSEQ;Visual Analog Scal,VAS; | — |
Countries
China
Contacts
Public ContactChen Gang
West China Hospital, Sichuan University
Outcome results
None listed