Kidney diseases (such as chronic kidney disease, acute kidney injury, etc.)
Conditions
Interventions
Kidney Tumor group:None
Health Control group:None
Sponsors
Shanghai Fourth People's Hospital Affiliated to Tongji University
Eligibility
Sex/Gender
All
Age
18 Years to No maximum
Inclusion criteria
Inclusion criteria: 1. Inclusion criteria for healthy volunteers: (1) Laboratory test results show normal serum creatinine levels for renal function; (2) No history of kidney diseases, diabetes, hypertension or other conditions that affect renal function; (3) No history of exposure to nephrotoxic drugs in the recent period; (4) Have undergone kidney MRI examinations including ASL and (or) TDD-MRI and (or) T1 quantitative sequences. 2. Inclusion criteria for patients with kidney diseases: (1) Clinically diagnosed with kidney diseases (including acute kidney injury, chronic kidney disease, kidney tumors, and history of diabetes affecting renal function, etc.); (2) Age over 18 years old; (3) Undergoing renal biopsy for histopathological examination in the hospital; (4) Have undergone kidney MRI examinations including ASL and (or) TDD-MRI and (or) T1 quantitative sequences.
Exclusion criteria
Exclusion criteria: 1.There are contraindications for MRI examination or the image quality is poor, making it impossible to obtain quantitative parameters; 2. There are kidney malformations or severe hydronephrosis.
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| Renal Blood Flow (RBF);T1 value;Apparent Diffusion Coefficient (ADC);Diameter;Intracellular water diffusion coefficient (Vin);Extracellular Water Diffusion Coefficient (Dex);Cellularity; | — |
Secondary
| Measure | Time frame |
|---|---|
| Estimated Glomerular Filtration Rate (eGFR);Urine Albumin-Creatinine Ratio (UACR);Serum Creatinine (Scr);Degree of renal tubular atrophy (0-3 points);Percentage of interstitial fibrosis (%);Glomerular sclerosis rate (%); | — |
Countries
China
Contacts
Public ContactLuo Yu
Shanghai Fourth People's Hospital Affiliated to Tongji University
Outcome results
None listed