skin aging
Conditions
Interventions
Sponsors
Eligibility
Inclusion criteria
Inclusion criteria: 1. Healthy women in the age range 30-50 years; 2. The skin is in good condition, without any signs of allergy and inflammation; 3. No skin improvement and other related treatment; 4. Voluntarily participate in the study and sign the informed consent; 5. Cuticle water content <=50, elasticity <=0.6
Exclusion criteria
Exclusion criteria: 1. Any form of allergy on the skin; 2. Ongoing skin improvement and other related treatments; 3. Medical beauty or any type of skin surgical treatment within 3 months before enrollment; 4. Have genetic history, work and rest disorder, spicy diet and other bad habits.
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| Skin function; | — |
Secondary
| Measure | Time frame |
|---|---|
| Inflammatory factor;Oxidative stress factor;Gut microbiota;Gut metabolites;Blood metabolites; | — |
Countries
China
Contacts
Chinese PLA General Hosptial