Postoperative pain
Conditions
Interventions
Sham-taVNS:Sham-taVNS
Sponsors
The First Hospital Of Jiaxing
Eligibility
Sex/Gender
All
Age
18 Years to 85 Years
Inclusion criteria
Inclusion criteria: 1. Aged 18-75 years. 2. ASA physical status classification I-III;. 3. Scheduled for major abdominal surgery under general anesthesia, requiring postoperative monitoring in the AICU. 4. The expected stay in the AICU is approximately 24 hours;.
Exclusion criteria
Exclusion criteria: 1. History of vagus nerve-related disorders (such as vasovagal syncope);. 2. Severe arrhythmia or implantation of electronic devices such as cardiac pacemakers;. 3. There is skin breakage, infection, or deformity at the external ear stimulation site. 4. Long-term preoperative use of opioids or sedatives;. 5. Allergic to study-related drugs. 6. Pregnant or breastfeeding women.
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| Total opioid consumption (morphine equivalents) within 24 hours postoperatively.; | — |
Secondary
| Measure | Time frame |
|---|---|
| Incidence of delirium within 24 hours postoperatively.;Postoperative sedation medication requirements;Incidence of opioid-related complications within 24 hours postoperatively.;Adverse events associated with taVNS.;Postoperative 24-hour recovery quality score.;SPO2, MAP, HR, and blood gas analysis indicators before and after extubation.;First Night Postoperative Sleep Quality Rating (RCSQ).;The worst COPT and NRS pain scores within 24 hours postoperatively.; | — |
Countries
China
Contacts
Public ContactMingzi An
The First Hospital Of Jiaxing
Outcome results
None listed