Symptomatic Atherosclerotic Non-Acute Internal Carotid Artery Occlusion
Conditions
Interventions
SANICAO Patient Group:none
Sponsors
Shenzhen Second People's Hospital
Eligibility
Sex/Gender
All
Age
18 Years to No maximum
Inclusion criteria
Inclusion criteria: 1.Age > 18 years; 2.Unilateral internal carotid artery occlusion detected by MRA/CTA/DSA; 3.Time from vascular occlusion to treatment is more than 24 hours (confirmed by imaging or inferred from the responsible event); 4.A responsible event related to the ipsilateral internal carotid artery occlusion occurred within the past 12 months, including one or more of the following: ischemic stroke, TIA (transient ischemic attack), or transient monocular vision loss (patients with only dizziness or headache are considered asymptomatic); 5. mRS <= 3; 6.The patient and their family members are willing to participate in this trial and sign the informed consent form.
Exclusion criteria
Exclusion criteria: 1.Occlusion caused by the following non-atherosclerotic diseases: such as arterial dissection, large vessel vasculitis, moyamoya disease; vasculitis caused by herpes simplex virus, varicella-zoster virus, or other viruses; neurosyphilis; leptospiral vasculitis; any type of intracranial infection; radiation-induced vascular occlusion; fibromuscular dysplasia; sickle cell anemia, etc.; 2.History of primary intracranial or ventricular hemorrhage; 3;Active bleeding within the past 30 days or known bleeding tendency; 4.History of extracranial-intracranial bypass surgery and/or recanalization treatment for occluded vessels; 5.Coexisting severe diseases or organ failure of important organs such as the heart, liver, kidneys, or lungs; presence of tumors. 6.Pregnant or breastfeeding women
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| Modified Rankin Scale;National Institutes of Health Stroke Scale;Simple Mental State Screening Scale;Montreal Cognitive Assessment;Stroke Recurrence;Mortality; | — |
Secondary
| Measure | Time frame |
|---|---|
| Quality of Life Score,EQ-5D;Imaging Improvement;Utilization of Medical Resources; | — |
Countries
China
Contacts
Public ContactZhao Xingqi
Shenzhen Second People's Hospital
Outcome results
None listed