Cognitive Function in Adolescents with Depression and Non-Suicidal Self-Injury: A Study Using Neuropsychological Tools and P300

Status

Active, not recruiting

Phases

Early Phase 1

Study type

Observational

Source

ChiCTR

Registry ID

ChiCTR2500112738

Enrollment

Unknown

Registered

2025-11-19

Start date

2024-09-18

Completion date

Unknown

Last updated

2025-11-24

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Depressive disorder

Interventions

Group of Adolescents with Depression Accompanying NSSI Behavior:None

Group of adolescents with depression without NSSI behaviors:None

Healthy control group:None

Eligibility

Sex/Gender

All

Age

12 Years to 22 Years

Inclusion criteria

Inclusion criteria: 1. Inclusion Criteria for the Depression Group (1) Meeting DSM-5 diagnostic criteria for depressive disorder and non-suicidal self-injury; (2) Montgomery-Åsberg Depression Rating Scale (MADRS) score >=12; (3) Age 12–22 years, either sex; (4) Confirmed history of prior depressive episode via the Mini International Neuropsychiatric Interview (MINI); (5) Voluntary participation with signed informed consent. 2. Inclusion Criteria for the Control Group (1) Negative screening via standardized scales with no current or past psychiatric disorder; (2) Age 12–22 years, either sex; (3) Matched to the patient group on gender and educational level; (4) Voluntary participation with signed informed consent.

Exclusion criteria

Exclusion criteria: 1. Exclusion Criteria for the Depression Group (1) Presence of organic brain disease; (2) Severe physical illness, substance dependence, or psychotic symptoms; (3) History of manic episodes; (4) History of seizures or family history of seizures; (5) Intellectual disability preventing completion of assessments; (6) Current severe illness preventing completion of study tasks. 2. Exclusion Criteria for the Control Group (1) Presence of organic brain disease; (2) Severe physical illness, substance dependence, or psychotic symptoms; (3) Use of medications affecting cognitive function within the past month; (4) Alcohol or drug dependence; (5) Intellectual disability preventing completion of assessments.

Design outcomes

Primary

Measure	Time frame
Mental health-related data (including Montgomery-?sberg Depression Rating Scale scores and indicators of non-suicidal self-injury);Cognitive function;	—

Countries

China

Contacts

Public ContactLi Mengqian

Nanchang University First Affiliated Hospital

limengqian@126.com+1 587 909 8200

Outcome results

None listed

Source: ChiCTR (via WHO ICTRP) · Data processed: Feb 4, 2026