Gastrointestinal
Conditions
Interventions
Sponsors
Eligibility
Inclusion criteria
Inclusion criteria: 1. patients undergoing laparoscopic gastrointestinal oncological surgery with American Society of Anaesthesiologists (ASA) classification II-III were to be included. 2. Age range: 18 years old = 4. 5. The patient or his/her family can understand the study, voluntarily sign the informed consent form, and are willing to comply with the requirements of the trial protocol.
Exclusion criteria
Exclusion criteria: 1. Those who are allergic or contraindicated to benzodiazepines, opioids, cypropofol, flumazenil, naloxone, tegretol fumarate and other drugs and their drug components. 2. Severe cardiac, pulmonary and renal insufficiency, combined with a variety of chronic diseases can not tolerate surgical anaesthesia. 3. Those with a history of alcoholism, opioid allergy or a history of abuse of such drugs. 4. Other conditions that the investigator considers unsuitable for enrolment. 5. Patients with recent neurological diseases or surgery.
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| Difference in resting/motor pain intensity within 24 hours after surgery; | — |
Secondary
| Measure | Time frame |
|---|---|
| First time to remedy analgesia;Total opioid consumption;Postoperative recovery indicators;Security indicators; | — |
Countries
China
Contacts
The First Affiliated Hospital Of USTC