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Study on the Effect and Mechanism of Parental Folic Acid Supplementation on Atherosclerosis in Offspring

Study on the Effect and Mechanism of Parental Folic Acid Supplementation on Atherosclerosis in Offspring

Status
Active, not recruiting
Phases
Unknown
Study type
Observational
Source
ChiCTR
Registry ID
ChiCTR2500112708
Enrollment
Unknown
Registered
2025-11-18
Start date
2025-11-18
Completion date
Unknown
Last updated
2025-11-24

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Atherosclerosis

Interventions

Male observation group:None

Sponsors

Harbin Medical University
Lead Sponsor

Eligibility

Sex/Gender
Male
Age
18 Years to No maximum

Inclusion criteria

Inclusion criteria: 1. Adult male (age >= 18) 2. All indicators of sperm routine examination are normal, including sperm quantity, sperm vitality, sperm morphology, sperm survival rate, and pH value

Exclusion criteria

Exclusion criteria: 1. Fever, infectious diseases, gastrointestinal diseases 2. Patients with combined liver and gallbladder diseases, malignant tumors, endocrine disorders, and other autoimmune diseases, as well as severe damage to important organs such as liver, liver, brain, and kidneys 3. Take folic acid antagonists such as methotrexate within 4 weeks before enrollment

Design outcomes

Primary

MeasureTime frame
Relative expression of key tsRNAs;Serum folate and its metabolite levels;—

Countries

China

Contacts

Public ContactHan Tianshu

Harbin Medical University

glacier@hrbmu.edu.cn+86 157 7660 7470

Outcome results

None listed

Source: ChiCTR (via WHO ICTRP) · Data processed: Feb 4, 2026