type II diabetes
Conditions
Interventions
GLP-1RA group and DPP-4i treatment group:None
Sponsors
Tianjin Medical University Chu Hsien-I Memorial Hospital & Institute of Endocrinology
Eligibility
Sex/Gender
All
Age
18 Years to 85 Years
Inclusion criteria
Inclusion criteria: 1. Diagnosed as a T2DM patient based on ICD10 encoding E11.900; 2. Age >= 18 years old; 3. The patient was treated with GLP-1RA or DPP-4i for more than 12 months from January 1, 2016 to December 31, 2024; 4. The patient has a history of CVD or cardiovascular risk factors before initiating treatment with GLP-1RA or DPP-4i.
Exclusion criteria
Exclusion criteria: 1. Pregnancy or type 1 diabetes HIV; 2. The patient experienced acute cardiovascular events three months before starting treatment with GLP-1RA or DPP-4i, including cerebrovascular disease (cerebral hemorrhage, cerebral infarction, subarachnoid hemorrhage, transient ischemic attack); New or recurrent non fatal coronary artery disease (myocardial infarction, unstable angina); Arteriosclerotic diseases that require hospitalization (aneurysms, arterial dissections, arterial occlusive disease).
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| 3P-MACE (All cause mortality, non fatal myocardial infarction, non fatal stroke); | — |
Secondary
| Measure | Time frame |
|---|---|
| Renal composite endpoint;Coronary revascularization;Hospitalized for unstable angina;Hospitalized for heart failure; | — |
Countries
China
Contacts
Public ContactLiming Chen
Tianjin Medical University Chu Hsien-I Memorial Hospital & Institute of Endocrinology
Outcome results
None listed