Knee arthroscopy
Conditions
Interventions
Group O:30 minutes before the end of surgery, administer an intravenous injection of oliceridine 1.5 mg and ondansetron 4 mg. Immediately after entering the PACU, perform PCIA, prepare the analgesia p
Group S:30 minutes before the end of surgery, 7.5 ug of sufentanil and 4 mg of ondansetron were administered intravenously. Immediately after entering the PACU, PCIA was performed, and the analgesic p
Sponsors
Longhua District People's Hospital, Shenzhen
Eligibility
Sex/Gender
All
Age
18 Years to 65 Years
Inclusion criteria
Inclusion criteria: 1. Age 18-65 years; 2. ASA classification I - III; 3. Understand and sign the informed consent; 4. Planned elective knee arthroscopic surgery; 5. BMI 18-28 kg/m^2.
Exclusion criteria
Exclusion criteria: 1. Individuals with severe cardiopulmonary dysfunction. 2. Individuals with abnormal electrocardiograms (e.g., prolonged QT interval). 3. Individuals with neurological or psychiatric disorders or a history thereof. 4. Patients with chronic pain, neuropathic pain, or a history of long-term analgesic use and alcohol abuse. 5. History of opioid allergy. 6. Use of medications that may affect analgesic response (central alpha-adrenergic agonists, antiepileptic drugs, nerve stimulants, antidepressants, or antipsychotics), without a fixed dose administered >=30 days preoperatively. 7. Recent receipt of other related surgeries that may affect study results.
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| Postoperative recovery quality;The occurrence of perioperative adverse events;The use of remedial drugs;The effective number of compressions of the analgesic pump and the total number of compressions; | — |
Secondary
| Measure | Time frame |
|---|---|
| Postoperative recovery quality;Pain score; | — |
Countries
China
Contacts
Public ContactKuang Xin
People's Hospital of Longhua District, Shenzhen, Guangdong Province
Outcome results
None listed