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Artificial Intelligence–Enabled Telerehabilitation for Chronic Nonspecific Neck Pain: A Multicenter Randomized Controlled Trial

Design and Application of an AI-Based Digital Therapeutic System for Conservative Treatment of Cervical Spondylosis

Status
Recruiting
Phases
Early Phase 1
Study type
Interventional
Source
ChiCTR
Registry ID
ChiCTR2500112693
Enrollment
Unknown
Registered
2025-11-18
Start date
2025-03-25
Completion date
Unknown
Last updated
2025-11-24

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Chronic Nonspecific Neck Pain

Interventions

conducted three times per week, approximately 30 minutes per session, for 24 weeks.
Telerehabilitation-Based Exercise Group:Home-based standardized training identical to the outpatient program, delivered through a telerehabilitation application with exercise demonstrations, reminders
performed three times per week, approximately 30 minutes per session, for 24 weeks.

Sponsors

Peking Union Medical College Hospital
Lead Sponsor

Eligibility

Sex/Gender
All
Age
18 Years to 60 Years

Inclusion criteria

Inclusion criteria: 1. Age: 18–60 years. 2. Condition: chronic nonspecific neck pain for =3 months. 3. Baseline thresholds: NDI =15/50 and NPRS (24-hour or 7-day average) =3/10. 4. Medical clearance: deemed clinically safe to participate in exercise-based rehabilitation. 5. Digital access: able to use a smartphone and willing to use/learn the study app;

Exclusion criteria

Exclusion criteria: 1. Surgery/trauma: prior cervical spine surgery; major cervical trauma or radiologic instability within 12 months. 2. Surgical/red-flag indications: progressive neurologic deficit or myelopathy; severe canal stenosis or lesions requiring surgery; active infection, tumor, or acute instability. 3. Structural/inflammatory disorders: inflammatory spondyloarthropathy; moderate–severe congenital/acquired deformity; symptomatic neural compression. 4. Serious systemic/psychiatric conditions: uncontrolled major organ disease; severe psychiatric illness or cognitive impairment compromising adherence. 5. Pregnancy or lactation. 6. Recent confounding care: initiation or substantial modification of cervical-related rehabilitation/physical therapy or interventional analgesia within 4–6 weeks before enrollment. 7. Other: interventional trial participation within 3 months; communication/device limitations or anticipated poor adherence precluding assessments or app use.

Design outcomes

Primary

MeasureTime frame
Neck Disability Index, NDI;

Secondary

MeasureTime frame
Numeric Pain Rating Scale, NPRS;EuroQol 5-Dimension 5-Level Questionnaire, EQ-5D-5L;Cervical Range of Motion, ROM;

Countries

China

Contacts

Public ContactCai Siyi

Peking Union Medical College Hospital

19904030811@163.com+86 199 0403 0811

Outcome results

None listed

Source: ChiCTR (via WHO ICTRP) · Data processed: Feb 4, 2026