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The Mechanism of lncRNA MALAT1 in Promoting Osteogenic Differentiation of Human Periodontal Ligament Stem Cells

The Mechanism of lncRNA MALAT1 in Promoting Osteogenic Differentiation of Human Periodontal Ligament Stem Cells

Status
Active, not recruiting
Phases
Unknown
Study type
Observational
Source
ChiCTR
Registry ID
ChiCTR2500112668
Enrollment
Unknown
Registered
2025-11-18
Start date
2025-11-18
Completion date
Unknown
Last updated
2025-11-24

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Periodontitis

Interventions

Premolars observation group:None

Sponsors

Beijing Stomatological Hospital , Capital Medical University
Lead Sponsor

Eligibility

Sex/Gender
All
Age
18 Years to 22 Years

Inclusion criteria

Inclusion criteria: 1.Patients requiring extraction of first or second premolars for orthodontic reasons. 2.Aged 18-22 years, regardless of gender.

Exclusion criteria

Exclusion criteria: 1.Clinical examination and X-ray images indicate abnormal root development of the premolar and its adjacent teeth (one mesial and one distal), or the presence of significant caries, pulpitis, apical periodontitis, or periodontitis. 2.Patients with systemic diseases, infectious diseases, or those who are pregnant or lactating. 3.Individuals with mental or intellectual impairments.

Design outcomes

Primary

MeasureTime frame
Gene expression level;—

Countries

China

Contacts

Public ContactYingzhi Gu

Beijing Stomatological Hospital , Capital Medical University

drguyingzhi@163.com+86 10 5709 9222

Outcome results

None listed

Source: ChiCTR (via WHO ICTRP) · Data processed: Feb 4, 2026