Benign Prostatic Hyperplasia
Conditions
Interventions
OFA:Anesthesia Induction:Midazolam: 0.05 mg/kg IV
Esketamine: 0.5 mg/kg IV
Propofol: 1.5-2.0 mg/kg IV
Rocuronium: 0.6 mg/kg IV
Anesthesia Maintenance:Dexmedetomidine: 0.1-0.3 µg/kg/min IV
Propofol: 5-7 mg/kg/h IV
Esketamine: 0.3-0.5 mg/kg/h IV
Control Group:Anesthesia Induction:Midazolam: 0.05 mg/kg IV
Sufentanil: 0.2-0.4 µg/kg IV
Propofol: 1.5-2.0 mg/kg IVRocuronium: 0.6 mg/kg IV
Anesthesia Maintenance:Propofol: 5-7 mg/kg/h IV
Remifentanil: 8-10 µg/kg/h IV
Sponsors
Huaihe Hospital of Henan University
Eligibility
Sex/Gender
All
Age
65 Years to 85 Years
Inclusion criteria
Inclusion criteria: Inclusion criteria:? aged 65-85 years, body mass index (BMI) of 18-30 kg/m^2, and American Society of Anesthesiologists (ASA) physical status classification of II-III.
Exclusion criteria
Exclusion criteria: 1.Patients with preoperative unconsciousness, inability to provide informed consent, or communication difficulties. 2.Patients with a history of allergy to the investigational drugs. 3.Patients who refused to cooperate. 4.Patients with severe cardiac or pulmonary diseases, craniocerebral injury, or psychiatric disorders. 5.Patients with uncontrolled hypertension
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| Occurrence of postoperative delirium; | — |
Secondary
| Measure | Time frame |
|---|---|
| MAP;Heart rate;Opioid dosage;Utilization rate of vasoactive drugs;Emergence time;Rescue analgesia rate;VAS score; | — |
Countries
China
Contacts
Public ContactQing YANG
Huaihe Hospital of Henan University, Gulou District, Kaifeng City, Henan Province, China
Outcome results
None listed