Cesarean scar pregnancy
Conditions
Interventions
Adjunct trophoblastic microcirculation occlusion followed by ultrasound-guided vacuum aspiration with hysteroscopy group:None
Adjunct trophoblastic microcirculation occlusion followed by ultrasound-guided vacuum aspiration without hysteroscopy group:None
Sponsors
Hangzhou Women's Hospital
Eligibility
Sex/Gender
Female
Inclusion criteria
Inclusion criteria: 1.A history of cesarean delivery and a positive pregnancy test result; 2.Gestational age less than 11 weeks; 3.Transvaginal ultrasound (TVUS) imaging indicating CSP according to the diagnostic criteria: i) an empty uterine cavity and cervical canal were observed; ii) gestational sac was embedded in the anterior isthmus of lower segment of uterus, which may or may not exhibit fetal cardiac activity; iii) thinner or even absent myometrium of the anterior wall of the uterus at the attachment site of the gestational sac; iv) the Doppler ultrasound revealed functional trophoblastic circulation surrounding the gestation sac; v) the gestational sac could extend towards the uterine cavity as pregnancy progressed, but the placenta stayed anchored in the area of the scar in its initial site of implantation; 4.The patients were treated with TMO.
Exclusion criteria
Exclusion criteria: 1.Patients undergoing direct vaginal removal or laparotomy or laparoscopic removal of the pregnancy; 2.Contraindications for curettage or hysteroscopy, such as acute inflammation or temperature over 38?; 3.Patients with severe diseases in the liver, kidney, heart, or lung; 4.Allergy to the ultrasonic contrast agent or lauromacrogol; 5.Unable to cooperate or tolerate with TMO treatment; 6.Unstable vital signs or massive vaginal bleeding before TMO treatment.
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| Success rate of treatment; | — |
Secondary
| Measure | Time frame |
|---|---|
| Serum level of human chorionic gonadotropin;Time for menstruation recovery;Disappearance time of intrauterine mass;Intraoperative blood loss;Number of uterine balloon compression;Number of persistent cesarean scar pregnancy;Hospital stay;Hospitalization cost;Number of re-pregnancies;Pregnancy outcome; | — |
Countries
China
Contacts
Public ContactWenchao Sun
Hangzhou Women's Hospital
Outcome results
None listed