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Effect of Lung Protective Ventilation Strategy on Intraocular Pressure in Patients Undergoing Laparoscopic Myomectomy in the Trendelenburg Position

Effect of Lung Protective Ventilation Strategy on Intraocular Pressure in Patients Undergoing Laparoscopic Myomectomy in the Trendelenburg Position

Status
Active, not recruiting
Phases
Unknown
Study type
Interventional
Source
ChiCTR
Registry ID
ChiCTR2500112612
Enrollment
Unknown
Registered
2025-11-17
Start date
2025-12-01
Completion date
Unknown
Last updated
2025-11-24

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

None

Interventions

Lung-protective ventilation strategy group:Lung-protective ventilation strategies were adopted during the operation
Conventional ventilation group:Traditional ventilation methods

Sponsors

No. 980 Hospital, Joint Logistics Support Force, People's Liberation Army
Lead Sponsor

Eligibility

Sex/Gender
Female
Age
18 Years to 65 Years

Inclusion criteria

Inclusion criteria: 1. The patient's preoperative pulmonary function or arterial blood gas analysis was normal; 2. No preoperative complications of ophthalmic diseases or history of ophthalmology-related surgeries; 3. Age 18-65 years old; 4. BMI<=30kg/m^2; 5. ASA I-II grade; 6. Voluntarily participated in this study and signed the informed consent form.

Exclusion criteria

Exclusion criteria: 1. Suffering from ophthalmic diseases or having a history of relevant ophthalmic surgeries; 2.There are obvious cardiovascular and cerebrovascular diseases or other serious systemic diseases; 3. The patient has a history of asthma or long-term smoking; 4. Patients with difficult airways such as thoracic deformity and scoliosis; 5.Having taken any medication that causes an increase or decrease in intraocular pressure within 14 days; 6. Those who have difficulty expressing, communicating and understanding; 7. The patient or their family members refuse.

Design outcomes

Primary

MeasureTime frame
The intraocular pressure (IOP) value of both eyes after 45 minutes of the Trenberg position;

Secondary

MeasureTime frame
The intraocular pressure (IOP) values of both eyes at the completion of tracheal intubation during anesthesia induction;The intraocular pressure (IOP) values of both eyes when establishing pneumoperitoneum;The immediate intraocular pressure (IOP) value of both eyes in the Trenberg position;The intraocular pressure (IOP) value of both eyes in the 20-minute Trenberg position;Restore the immediate intraocular pressure (IOP) values of both eyes to the horizontal position;Restore the intraocular pressure (IOP) values of both eyes to the horizontal position for 15 minutes;Total time spent in Tronberg's postures;Anesthesia time;The end-respiratory carbon dioxide values at the above five time points;

Countries

China

Contacts

Public ContactWu Yu

No. 980 Hospital, Joint Logistics Support Force, People's Liberation Army

vwuyuv@163.com+86 186 3348 7638

Outcome results

None listed

Source: ChiCTR (via WHO ICTRP) · Data processed: Feb 4, 2026