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Evaluating the Efficacy and Safety of Transmucosal Partial Lateral Internal Sphincterotomy for Chronic Anal Fissure: A Retrospective Study

Evaluating the Efficacy and Safety of Transmucosal Partial Lateral Internal Sphincterotomy for Chronic Anal Fissure: A Retrospective Study

Status
Active, not recruiting
Phases
Unknown
Study type
Observational
Source
ChiCTR
Registry ID
ChiCTR2500112604
Enrollment
Unknown
Registered
2025-11-17
Start date
2025-12-01
Completion date
Unknown
Last updated
2025-11-24

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Chronic anal fissure, characterized by periodic anal pain, hematochezia (blood in stool), and fear of defecation.

Interventions

Observation group:None

Sponsors

Shanghai General Hospital
Lead Sponsor

Eligibility

Sex/Gender
All
Age
18 Years to 65 Years

Inclusion criteria

Inclusion criteria: 1. Age between 18 and 65 years; 2.Diagnosis of chronic anal fissure (disease course > 6 weeks, accompanied by typical signs such as sentinel pile and hypertrophied anal papilla); 3.Failure of conservative treatment (for at least 4 weeks); 4.Underwent either the TM-PLIS or LIS procedure at our hospital between January 2022 and June 2025; 5.Availability of complete pre-operative and post-operative medical records.

Exclusion criteria

Exclusion criteria: 1. Patients with comorbid conditions such as perianal abscess, complex anal fistula, Crohn's disease, tuberculosis, or tumors; 2. Patients with a history of prior anorectal surgery; 3. Women who are pregnant or lactating; 4. Patients with concomitant neurological disorders or diabetic peripheral neuropathy; 5. Patients with missing key outcome data will be excluded; those with missing partial data may be handled using imputation methods.

Design outcomes

Primary

MeasureTime frame
Anal fissure healing rate;

Countries

China

Contacts

Public ContactLiu Yunlong

Shanghai General Hospital

dr.yunlong@163.com+86 21 63240090

Outcome results

None listed

Source: ChiCTR (via WHO ICTRP) · Data processed: Feb 4, 2026