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Oxycodone versus Sufentanil for Postoperative Analgesia in Transnasal Endoscopic Surgery: A Randomized Controlled Trial

Oxycodone versus Sufentanil for Postoperative Analgesia in Transnasal Endoscopic Surgery: A Randomized Controlled Trial

Status
Active, not recruiting
Phases
Unknown
Study type
Interventional
Source
ChiCTR
Registry ID
ChiCTR2500112599
Enrollment
Unknown
Registered
2025-11-17
Start date
2025-11-30
Completion date
Unknown
Last updated
2025-11-24

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Cases with sinusitis, nasal septal deviation

Interventions

Intervention Group:Oxycodone
Control Group:Sufentanil

Sponsors

Xuanwu Hospital, Capital Medical University
Lead Sponsor

Eligibility

Sex/Gender
All
Age
18 Years to No maximum

Inclusion criteria

Inclusion criteria: 1.Patients scheduled for elective transnasal endoscopic surgery; 2.Patients of either sex; 3.ASA I-III; 4.Age >= 18 years; 5.Provision of signed informed consent; 6.Agreement to use a postoperative patient-controlled analgesia pump.

Exclusion criteria

Exclusion criteria: 1.Patients with opioid dependence; 2.Patients with a known allergy to any drug involved in the anesthesia protocol; 3.Patients combined with major organ dysfunction; 4.Patients with contraindications to nonsteroidal anti-inflammatory drugs; 5.Patients with poor therapeutic compliance or inability to cooperate with the study.

Design outcomes

Primary

MeasureTime frame
The incidence of moderate-to-severe pain within 48 hours postoperatively;

Secondary

MeasureTime frame
Sedation scores;Duration of postoperative pain in patients;Postoperative sleep quality;The number of PCA demands within 48 hours postoperatively;The incidence of adverse events (nausea and vomiting) within 48 hours after surgery.;Patient Satisfaction;Comparison of Intraoperative Parameters;

Countries

China

Contacts

Public ContactTianlong Wang

Xuanwu Hospital, Capital Medical University

w_tl5595@hotmail.com+86 10 83199333

Outcome results

None listed

Source: ChiCTR (via WHO ICTRP) · Data processed: Feb 4, 2026