female infertility
Conditions
Interventions
12-hour time-restricted feeding group:beginning 10 weeks before ART, participants followed a Mediterranean-style dietary pattern emphasizing vegetables, high-quality proteins, and whole grains with re
calorie-restricted traditional weight loss group:calorie-restricted traditional weight loss:beginning 10 weeks before ART, participants followed a calorie-restricted diet within1200-1500kcal per day
control group:Only standardised advice and education identical to that provided to the intervention group, with no other interventions.
Sponsors
Shengjing Hospital of China Medical University
Eligibility
Sex/Gender
Female
Age
20 Years to 38 Years
Inclusion criteria
Inclusion criteria: 1. aged 20-38 years; 2.40kg/m^2>=BMI>=24kg/m^2; 3.with strong desire to lose weight and be pregnant; 4.AMH>=0.5ng/ml;
Exclusion criteria
Exclusion criteria: 1. Long-term night work or insomnia; 2. Severe metabolic diseases (hyperthyroidism, hypothyroidism, Cushing's syndrome, pituitary amenorrhea, etc.); 3.Gastrointestinal, cardiovascular diseases; 4.Smoking, alcoholism; 5.Azoospermia; 6.Endometriosis, uterine synechiae, myomas affecting the endometrium, recurrent biochemical pregnancies, repeated implantation failure, and recurrent spontaneous abortion (three or more consecutive miscarriages before 28 weeks of gestation). 7.The endometrial thickness during the ovulatory phase is less than 6 mm. 8.Donor egg recipient; 9.Severe immunological disorders (such as systemic lupus erythematosus, antiphospholipid syndrome, etc.);
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| cumulative live birth rate; | — |
Secondary
| Measure | Time frame |
|---|---|
| clinical pregnancy rate;miscarriage rate;LH?FSH?E2?P,insulin,glucose,TG,HDL,LDL,auxin;weight,body fat; | — |
Countries
China
Contacts
Public Contacttanjichun
Shengjing Hospital of China Medical University
Outcome results
None listed