Comparison of postoperative Analgesia given Sufentanil or Tegileridine in Laparoscopic Cholecystectomy, a prospective, randomized, controlled, blinded study

Status

Active, not recruiting

Phases

Phase 4

Study type

Interventional

Source

ChiCTR

Registry ID

ChiCTR2500112585

Enrollment

Unknown

Registered

2025-11-17

Start date

2025-12-01

Completion date

Unknown

Last updated

2025-11-24

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Cholecystolithiasis, cholecystitis

Interventions

Sufentanil Group:After anesthesia induction and the start of the operation, patients randomly assigned to the sufentanil group were administered 5 µg of sufentanil (in 20ml normal saline) via infusion

Tegileridine Group:After induction of anesthesia and the start of the operation, patients randomly assigned to the Tegileridine group were given a pump infusion of 0.75 to 1 mg of Tegileridine (0.015

Eligibility

Sex/Gender

All

Age

18 Years to 65 Years

Inclusion criteria

Inclusion criteria: 1. ASA physical status classification I-II; 2. Age 18 ~ 65 years old; 3. Body Weight 50 ~ 90 kg and BMI 18 ~ 30 kg/?.

Exclusion criteria

Exclusion criteria: 1. Abnormal coagulation function; 2. PLT < 80*10^9/L; 3. History of chronic pain; 4. Abused of opioids; 5. Intestinal obstruction; 6. History of anxiety and/or depression; 7. Cannot comunicate normally; 8. Participate in another clinical study; 9. Subjects or their family members refused.

Design outcomes

Primary

Measure	Time frame
The incidence of moderate to severe pain 24 hours after the operation;	—

Secondary

Measure	Time frame
Recovery time from anesthesia;Length of stay in PACU;The incidence of emergency agitation;Pain score arriving at PACU;Pain score discharging from PACU;Pain scores at 6, 12, 48 hours after the operation;Opioid consumption in morphine milligram equivalents (MME) postoperative 48 hours;The first anal exhaust time;The incidence of PONV;The incidence of urinary retention;The incidence of pain postoperative 3 months;	—

Measure

Time frame

Recovery time from anesthesia;Length of stay in PACU;The incidence of emergency agitation;Pain score arriving at PACU;Pain score discharging from PACU;Pain scores at 6, 12, 48 hours after the operation;Opioid consumption in morphine milligram equivalents (MME) postoperative 48 hours;The first anal exhaust time;The incidence of PONV;The incidence of urinary retention;The incidence of pain postoperative 3 months;

—

Countries

China

Contacts

Public ContactYue Caibao

Puyang Oil Field General Hospital

yuecb1987@163.com+86 150 3931 5428

Outcome results

None listed

Source: ChiCTR (via WHO ICTRP) · Data processed: Feb 4, 2026