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Mechanism of Bone Specific Invasion of Renal Cell Carcinoma

Study on The Mechanism of Bone Specific Invasion of Renal Cell Carcinoma: A Single Center, Ambispective Cohort Study

Status
Active, not recruiting
Phases
Early Phase 1
Study type
Observational
Source
ChiCTR
Registry ID
ChiCTR2500112572
Enrollment
Unknown
Registered
2025-11-17
Start date
2025-11-30
Completion date
Unknown
Last updated
2025-11-24

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Renal cell carcinoma

Interventions

Sponsors

Peking University Third Hospital
Lead Sponsor

Eligibility

Sex/Gender
All
Age
18 Years to No maximum

Inclusion criteria

Inclusion criteria: 1. Age >= 18 years old; 2. Diagnosed with renal cell carcinoma by postoperative histopathological examination; 3. The patient and his/her family have signed the informed consent form for this study.

Exclusion criteria

Exclusion criteria: 1. Those with other malignant tumors except for renal cell carcinoma; 2. Those with two or more distant organ metastases at the time of surgery; 3. Those with substandard tissue pathology samples; 4. Those who suffer serious consequences or death due to anesthesia accidents during the operation.

Design outcomes

Primary

MeasureTime frame
Bone metastasis free survival;

Secondary

MeasureTime frame
The level of ANXA2 protein in plasma exosomes;The level of ANXA2 protein in tissue exosomes;ANXA2 expression of ANXA2 in tumor tissue;Differentiation markers expression of BMSC;

Countries

China

Contacts

Public ContactShudong Zhang

Peking University Third Hospital

zhangshudong@bjmu.edu.cn+86 156 1196 3326

Outcome results

None listed

Source: ChiCTR (via WHO ICTRP) · Data processed: Feb 4, 2026